Mesotherapy: Custom Vitamin Cocktails for Skin & Hair
Our skin and hair are the most important external indicators of our health and youth. However, over time, due to environmental factors (sun, pollution), stress, hormonal changes, and nutritional deficiencies, skin can become dull, dry, lose its elasticity, develop spots, and hair can weaken and begin to fall out. While the creams and serums we use can only affect the top layer of the skin, the essential nutrients need to reach the deeper layers or the hair follicles. Mesotherapy is a targeted micro-injection method that addresses this exact need.
Mesotherapy is the process of directly injecting vitamins, minerals, amino acids, hyaluronic acid, and other growth factors that your skin or scalp needs into its middle layer (the mesoderm), using very fine needles. This is a highly effective treatment method that nourishes from within, repairs, revitalizes the skin, and strengthens hair follicles. At his clinic in Istanbul, Assoc. Prof. Dr. Yalçın Bayram meticulously analyzes your skin and hair type to ensure you achieve the most natural and effective results with mesotherapy cocktails prepared specifically for you.
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What is Mesotherapy and How Does It Work?
Mesotherapy is derived from the words "mesoderm" (middle skin) and "therapy" (treatment). Its basic principle is to deliver active ingredients, targeted at solving a specific problem, directly into the problematic area in small doses. This allows:
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Targeted Treatment: Medications or nutrients are delivered directly to the area needed (e.g., the dermis layer where a wrinkle is, or a weakened hair follicle) without being diluted or losing effectiveness in the bloodstream.
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Biological Stimulation: The act of numerous micro-injections itself creates a "micro-trauma" effect, triggering the skin's natural healing mechanisms and collagen production.
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Cellular Nutrition: The injected vitamins, minerals, and amino acids accelerate the metabolism of skin cells or hair follicles, aiding their repair and encouraging healthier function.
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Hydration: Formulas containing Hyaluronic Acid, in particular, increase the skin's water-retention capacity, providing deep hydration and plumpness.
Application Areas of Mesotherapy: Tailored Solutions for Every Need
Mesotherapy is an extremely flexible treatment method and offers solutions to many different aesthetic and medical problems, depending on the content of the "cocktail" used.
1. Facial Mesotherapy (Skin Rejuvenation and Revitalization)
This is the most popular application area. It is performed to combat the signs of aging, improve skin quality, and achieve a brighter, more vibrant appearance.
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Used For: Dullness, dryness, fine lines, loss of elasticity, uneven skin tone, tired expression.
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Ingredients: Typically contains skin-nourishing and repairing components like Hyaluronic Acid, vitamins (A, C, E, B-complex), minerals, antioxidants, amino acids, and Salmon DNA.
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Popular Concepts:
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"Youth Booster": Usually contains pure, non-cross-linked, high-concentration Hyaluronic Acid. Its main purpose is to provide intense moisture, smooth fine lines, and trigger the skin's own collagen production.
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"Salmon DNA": Contains polynucleotides derived from salmon sperm. It supports cell regeneration by increasing protein synthesis, repairing, and firming the skin.
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"Paris Glow" (NCTF 135HA): A very rich anti-aging cocktail containing over 50 vitamins, minerals, amino acids, and coenzymes in addition to hyaluronic acid. It gives the skin an instant glow, vibrancy, and "radiance."
2. Hair Mesotherapy (Hair Loss Treatment)
This is one of the most effective medical treatments to reduce hair loss in both women and men, strengthen existing hair, and support new hair growth.
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Used For: Seasonal hair loss, stress-related shedding, hormonal hair loss (as a supportive treatment for Androgenetic Alopecia), weak, lifeless, and slow-growing hair.
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Ingredients: Special cocktails containing vitamins that nourish hair follicles (especially Biotin, B vitamins), minerals (Zinc, Selenium), amino acids (Arginine, Cysteine), circulation enhancers, and growth factors are used.
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Effect: Increases blood circulation in the scalp, nourishes the follicles, extends the hair's life cycle, and significantly reduces hair loss.
3. Under-Eye Mesotherapy (Dark Circles and Brightening)
Used to treat under-eye dark circles, fine lines, and a tired expression.
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Ingredients: Special cocktails formulated for this area are used, containing ingredients that regulate circulation (Vitamin C, Rutin, Gingko Biloba) and reduce pigmentation to brighten the skin. They often contain low-concentration Hyaluronic Acid.
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Difference from "Tear Trough Fillers": While under-eye light filler focuses on filling hollows, under-eye mesotherapy focuses on improving skin quality, lightening color, and treating fine lines. They can sometimes be combined for the best results.
4. Body Mesotherapy (Cellulite and Localized Fat Reduction)
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Cellulite Treatment: Special cocktails are injected into the cellulite-affected area to increase circulation, trigger fat cell breakdown (lipolysis), and strengthen connective tissue. It improves the "orange peel" appearance.
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Localized Fat Reduction (Lipolytic Mesotherapy): Fat-dissolving (lipolytic) substances (like phosphatidylcholine, deoxycholate) are injected into areas with small, stubborn fat deposits like the jowl (double chin), abdomen, or hips. However, it must be noted that mesotherapy is not a weight-loss method or an alternative to liposuction. It is effective only in very small and limited areas and usually requires multiple sessions.
5. Spot Treatment Mesotherapy (Hyperpigmentation)
Used to treat pigmentation problems such as sun spots, age spots, or melasma. Cocktails containing spot-lightening and melanin-inhibiting substances like Vitamin C, Tranexamic Acid, and Glutathione are injected.
The Mesotherapy Process: Personalized Cocktails
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Consultation and Analysis: Assoc. Prof. Dr. Yalçın Bayram first analyzes your skin or hair type, identifies your problem, and discusses your treatment goals with you.
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Cocktail Selection: Based on the analysis, a personalized mesotherapy cocktail containing the most suitable vitamins, minerals, amino acids, and other active ingredients for your specific needs is prepared or selected.
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Application: The area is cleansed, and an anesthetic cream is applied to numb it. Then, the prepared cocktail is injected into the middle layer of the skin or scalp (mesoderm) in small doses at 1-2 cm intervals, using very fine, short needles, either by hand or with a special "meso-gun". The procedure lasts 15 to 45 minutes, depending on the size of the area.
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Number and Frequency of Sessions: The effect of mesotherapy is generally cumulative, meaning it increases as sessions progress. A single session is not enough to achieve the desired result. Typically, 4 to 8 sessions are planned, depending on the area and severity of the problem. Session intervals may be 1-2 weeks initially, later reduced to once a month.
What to Pay Attention to After Mesotherapy
The recovery process after mesotherapy is generally very quick and comfortable.
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Slight redness, small bumps, or tiny bruises at the injection sites may be visible immediately after the procedure. These usually disappear on their own within a few hours to a few days.
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It is recommended not to wet the area, apply makeup, or expose it to excessive heat (hammam, sauna) or sun for the first 24 hours.
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Sunscreen use is crucial, especially after facial mesotherapy.
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It is recommended not to wash the hair for the first 1-2 days after hair mesotherapy.
Mesotherapy Costs 2025
Mesotherapy prices are determined per session based on several factors:
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Content and Brand of the Cocktail Used: The cost of a "Youth Booster" containing pure hyaluronic acid will differ from a "Paris Glow" with over 50 ingredients or a hair mesotherapy cocktail with special growth factors.
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Size of the Application Area: A full-face application will not be the same price as an application only under the eyes.
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Number of Sessions: Package programs (e.g., 4 or 6 sessions) are often more cost-effective than single-session prices.
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Expertise of the Provider: An application performed by a Plastic Surgery Specialist like Assoc. Prof. Dr. Yalçın Bayram, with his mastery of skin anatomy and product ingredients, makes a difference in your safety and the results you will achieve. A personalized treatment plan and pricing can only be determined after a detailed skin or hair analysis and consultation with Assoc. Prof. Dr. Yalçın Bayram.
Frequently Asked Questions About Mesotherapy
Is the mesotherapy procedure painful?
Pain is minimal thanks to anesthetic creams applied before the procedure. Since the injections are very superficial and made with very fine needles, it generally does not go beyond a slight stinging sensation. Applications, especially with a meso-gun, are even more comfortable.
When are mesotherapy results visible?
This depends on the area treated and the content of the cocktail.
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Facial Mesotherapy: A radiance and revitalization of the skin can be noticed even after the first session. However, the main effect (increased collagen, reduction in fine lines) usually appears after the 2nd or 3rd session and builds as the treatment progresses.
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Hair Mesotherapy: A reduction in hair loss is often noticed after the first few sessions. Visible new hair growth, however, may take 3 to 6 months due to the hair's natural growth cycle.
How long does the effect of mesotherapy last?
Mesotherapy is a treatment that improves the quality of the skin or hair follicles; it is not like a permanent filler or implant. To maintain the achieved effect, "touch-up" sessions are generally recommended every 3 to 6 months after the initial course is completed. This continuously supports the health of the skin and hair.
What is the difference between mesotherapy, fillers, and Botox?
Mesotherapy is like a "nutritional supplement" that improves skin quality and health; it delivers vitamins and minerals to the middle layer of the skin. Botox relaxes muscles to smooth dynamic wrinkles. Filler fills in lost volume. The three serve completely different purposes and are often used in combination for the best results.
Does hair mesotherapy really grow new hair?
The primary goal of hair mesotherapy is to strengthen existing hair follicles, stop hair loss, and make dormant, thin "vellus" hairs thicker, making the hair appear denser. It cannot bring back a completely dead and gone hair follicle. However, it can stimulate sleeping or weakened follicles, triggering some new hair growth. A density increase like that from a hair transplant should not be expected; it is more of a treatment to maintain and improve the current condition.
How does facial mesotherapy rejuvenate the skin?
It deeply hydrates with hyaluronic acid, fights free radicals with vitamins and antioxidants, and triggers collagen and elastin production with amino acids. As a result, the skin becomes brighter, firmer, more hydrated, smoother, and healthier. Fine lines are reduced, and the aging process slows down.
How many mesotherapy sessions are needed?
This depends entirely on the problem being treated and the individual's response. While 4-6 sessions are often sufficient for skin revitalization, hair loss or spot treatment may require 8-10 sessions. Session intervals also vary. Your doctor will create the most accurate plan for you.
Will there be bruising after mesotherapy?
Since many micro-injections are performed, tiny bruises may occur at the injection sites, especially in those with sensitive skin or who use blood thinners. These bruises usually disappear on their own within a few days and can be easily camouflaged with concealer.
